Prachatice (Czech pronunciation: [ˈpraxacɪtsɛ] ; German: Prachatitz) is a town in the South Bohemian Region of the Czech Republic. It has about 11,000 inhabitants. It is located in a hilly landscape in the Bohemian Forest Foothills.
Among the notable owners of the town were the noble families of Rosenberg (1501–1601), Eggenberg (1621–1719) and Schwarzenberg (1719–1848). The town has many Renaissance monuments. The historic town centre is well preserved and is protected as an urban monument reservation.