Hora Svatého Šebestiána (German: Sankt Sebastiansberg) is a municipality and village in Chomutov District in the Ústí nad Labem Region of the Czech Republic. It has about 400 inhabitants. Hora Svatého Šebestiána lies approximately 14 kilometres (9 mi) north-west of Chomutov, 59 km (37 mi) west of Ústí nad Labem, and 98 km (61 mi) north-west of Prague.