Chomutov (Czech pronunciation: [ˈxomutof] ; German: Komotau) is a city in the Ústí nad Labem Region of the Czech Republic. It has about 47,000 inhabitants, but there are almost 80,000 inhabitants in the city's wider metropolitan area. The city is located on the Chomutovka River. The history of Chomutov is connected with the Jesuits, who acted here from 1589 to 1773. However, the main development of the city occurred only in the 19th century thanks to industrialisation and lignite mining. The historic city centre is well preserved and is protected as an urban monument zone. Popular tourist destinations include Zoopark Chomutov, which is the largest zoo in the Czech Republic by area.